Title: Systematic Mapping of the Monkey Inferior Colliculus Reveals Enhanced Low
نویسندگان
چکیده
250 words) 21 We investigated the functional architecture of the inferior colliculus (IC) in rhesus 22 monkeys. We systematically mapped multiunit responses to tonal stimuli and noise in 23 the IC and surrounding tissue of six rhesus macaques, collecting data at evenly placed 24 locations and recording non-responsive locations to define boundaries. The results 25 show a modest tonotopically organized region (17 of 100 recording penetration 26 locations in 4 of 6 monkeys) surrounded by a large mass of tissue that, though 27 vigorously responsive, showed no clear topographic arrangement (68 of 100 penetration 28 locations). Rather, most cells in these recordings responded best to frequencies at the 29 low end of the macaque auditory range. The remaining 15 (of 100) locations exhibited 30 auditory responses that were not sensitive to sound frequency. Potential anatomical 31 correlates of functionally defined regions, and implications for midbrain auditory 32 prosthetic devices are discussed. 33
منابع مشابه
Systematic mapping of the monkey inferior colliculus reveals enhanced low frequency sound representation.
We investigated the functional architecture of the inferior colliculus (IC) in rhesus monkeys. We systematically mapped multiunit responses to tonal stimuli and noise in the IC and surrounding tissue of six rhesus macaques, collecting data at evenly placed locations and recording nonresponsive locations to define boundaries. The results show a modest tonotopically organized region (17 of 100 re...
متن کاملNeuronal activity in the inferior colliculus and bordering structures during vocalization in the squirrel monkey.
In four squirrel monkeys (Saimiri sciureus), the inferior colliculus, together with the neighboring superior colliculus, reticular formation, cuneiform nucleus and parabrachial area, were explored with microelectrodes, looking for neurons that might be involved in the discrimination between self-produced and external sounds. Vocalization was elicited by kainic acid injections into the periaqued...
متن کاملDescending projections to the inferior colliculus from the posterior thalamus and the auditory cortex in rat, cat, and monkey.
Projections from the posterior thalamus and medial geniculate body were labeled retrogradely with wheat germ agglutinin conjugated to horseradish peroxidase injected into the rat, cat, and squirrel monkey inferior colliculus. Neurons were found ipsilaterally in the (1) medial division of the medial geniculate body, (2) central gray, (3) posterior limitans nucleus, and the (4) reticular part of ...
متن کاملSpectrotemporal response properties of inferior colliculus neurons in alert monkey.
Because of its central position in the ascending auditory pathway, its large number of converging auditory brainstem inputs, and its fundamental role as a relay to auditory cortex and midbrain superior colliculus, the mammalian inferior colliculus (IC) is regarded pivotal for the integration of acoustic spectral-temporal cues to mediate sound-evoked behavior. However, detailed quantitative anal...
متن کامل